G-quadruplex DNA interactions, docking and cell photocytotoxicity research of porphyrin dyes
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- 作者：Ping Zhaoa ; zhaoping666@163.com" class="auth_mail" title="E-mail the corresponding author ; Min-Chao Liua ; Min Zhengb ; sourcabage@126.com" class="auth_mail" title="E-mail the corresponding author ; Shu-fang Jina ; Ding-tong Tanga ; Jiong Chena ; Yan-na Maa ; Jia-qi Lina ; Xia-hong Wanga ; Hong-jian Liua
- 关键词：Cationic porphyrins ; G-quadruplex DNA ; Spectral method ; Molecular dock ; Steric hindrance ; Photocytotoxicity
- 刊名：Dyes and Pigments
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：128
- 期：Complete
- 页码：41-48
- 全文大小：1608 K
文摘
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Novel expanded cationic porphyrin was successfully designed and synthesized.
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Spectral and Docking results show TPMPyP2 is more favorable in G4-DNA binding.
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TPMPyP2 is more potential as photochemotherapeutic agents.