A novel conformational B-cell epitope prediction method based on mimotope and patch analysis
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- 作者：Pingping Suna ; b ; c ; sunpp567@nenu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jialiang Qia ; c ; Yizhu Zhaoa ; c ; Yanxin Huangb ; Guifu Yanga ; young_nenu@163.com" class="auth_mail" title="E-mail the corresponding author ; Zhiqiang Mac ; mazq@nenu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yuxin Lib ; liyx486@nenu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Epitope prediction ; Mimotope ; Amino acids pairs ; Patch
- 刊名：Journal of Theoretical Biology
- 出版年：2016
- 出版时间：7 April 2016
- 年：2016
- 卷：394
- 期：Complete
- 页码：102-108
- 全文大小：644 K
文摘
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A novel epitope prediction method based on amino acid pairs and patch analysis.
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Predict epitopes based on AAPs from mimotopes and the surface patch.
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Gives out the sensitivity of 0.53, the specificity of 0.77, the ACC of 0.75
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Comparing with other methods, the sensitivity of the new method all has improvement.