An assessment of the anti-fatigue effects of ketamine from a double-blind, placebo-controlled, crossover study in bipolar disorder
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- 作者：Leorey N. Saligana ; saliganl@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author ; David A. Luckenbaughb ; luckenbd@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author ; Elizabeth E. Slonenab ; elizabeth.slonena@nih.gov" class="auth_mail" title="E-mail the corresponding author ; Rodrigo Machado-Vieirab ; rodrigo.machadovieira@nih.gov" class="auth_mail" title="E-mail the corresponding author ; Carlos A. Zarate Jr.b ; zaratec@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Fatigue ; Ketamine ; Depression ; Glutamate ; New therapeutics
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：194
- 期：Complete
- 页码：115-119
- 全文大小：557 K
文摘
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NMDA receptor inhibition as a potential therapeutic option for fatigue.
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The potential role of glutamatergic system in the pathophysiology and therapeutics of fatigue.
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The utility of NIH-BFI to measure changes in fatigue symptoms in a clinical trial.