MicroRNA-379-5p inhibits tumor invasion and metastasis by targeting FAK/AKT signaling in hepatocellular carcinoma
详细信息 查看全文
- 作者：Jing-Song Chena ; Hua-Shu Lib ; Jiong-Qiang Huanga ; Shi-Hao Donga ; Zhi-Jie Huanga ; Wei Yia ; Gao-Fang Zhana ; Ju-Tao Fenga ; Jian-cong Suna ; Xiao-Hui Huangc ; hxiaohui2006@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hepatocellular carcinoma ; Focal adhesion kinase ; Invasion ; Metastasis ; miR-379-5p
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 May 2016
- 年：2016
- 卷：375
- 期：1
- 页码：73-83
- 全文大小：3149 K
文摘
- class="listitem" id="list_ulist0010">
- class="label">•
miR-379-5p is significantly down-regulated in HCC.
- class="label">•
miR-379-5p can inhibit HCC invasion and metastasis.
- class="label">•
FAK is a direct target of miR-379-5p.
- class="label">•
miR-379-5p exerts its functions through inhibiting FAK/AKT signaling.
- class="label">•
miR-379-5p might be a potential therapeutic target and prognostic marker for HCC.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |