Mesenchymal Stem Cells from Wharton's Jelly and Amniotic Fluid
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- 作者：Marianne S. Joerger-Messerli ; PhDa ; b ; marianne.joerger@dkf.unibe.ch" class="auth_mail" title="E-mail the corresponding author ; Caterina Marx ; B Meda ; b ; caterina.marx@students.unibe.ch" class="auth_mail" title="E-mail the corresponding author ; Byron Oppliger ; MSca ; b ; byron.oppliger@dkf.unibe.ch" class="auth_mail" title="E-mail the corresponding author ; Martin Mueller ; MDa ; b ; c ; martin.mueller@insel.ch" class="auth_mail" title="E-mail the corresponding author ; Daniel V. Surbek ; MDa ; b ; daniel.surbek@insel.ch" class="auth_mail" title="E-mail the corresponding author ; Andreina Schoeberlein ; PhDa ; b ; andreina.schoeberlein@dkf.unibe.ch" class="auth_mail" title="E-mail the corresponding author
- 关键词：amniotic fluid ; mesenchymal stem cells ; regenerative potential ; Wharton's jelly
- 刊名：Best Practice & Research Clinical Obstetrics & Gynaecology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：31
- 期：Complete
- 页码：30-44
- 全文大小：335 K
文摘
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Wharton's jelly (WJ) and amniotic fluid (AF) are more primitive that adult mesenchymal stem cells (MSC), but not tumorigenic.
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Preclinical and clinical studies suggest the safe and efficacious use of WJ-MSCs and AF-MSCs in future stem cell therapies.
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WJ-MSCs and AF-MSCs are regenerative due to their migration, differentiation, secretome and immunomodulatory properties.