Inter- and intraobserver agreement of ADC measurements of lung cancer in free breathing, breath-hold and respiratory triggered diffusion-weighted MRI

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• 作者：Lei Cui^a ; ^b ; Jian-Bing Yin^b ; Chun-Hong Hu^a ; ^{drhuchunhong@163.com" class="auth_mail" title="E-mail the corresponding author} ; Shen-Chu Gong^b ; ^{gongshenchu@126.com" class="auth_mail" title="E-mail the corresponding author} ; Jun-Feng Xu^b ; Ju-Shun Yang^b
• 关键词：Lung cancer ; Diffusion-weighted imaging ; Apparent diffusion coefficient ; Observer agreement ; Reproducibility
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：September-October 2016
• 年：2016
• 卷：40
• 期：5
• 页码：892-896
• 全文大小：546 K

文摘

To prospectively evaluate the inter- and intraobserver agreement of apparent diffusion coefficient (ADC) measurements in free breathing, breath-hold, and respiratory triggered diffusion-weighted imaging (DWI) of lung cancer.

Methods

Twenty-two patients with lung cancer (tumor size > 2 cm) underwent DWIs (3.0 T) in three imaging methods. Lesion ADCs were measured twice by both of the two independent observers and compared.

Results

No statistical significance was found among methods, though respiratory-triggered DWI tended to have higher ADCs than breath-hold DWI. Great inter- and intraobserver agreement was shown.

Conclusion

ADCs had good inter- and intraobserver agreement in all three DWI methods.