Mechanochemical approach for the capping of mixed core CdS/ZnS nanocrystals: Elimination of cadmium toxicity

详细信息    查看全文

• 作者：Zdenka Bujňá ; ková ; ^a ; ^{bujnakova@saske.sk" class="auth_mail" title="E-mail the corresponding author} ; Matej Balá ; ž^a ; ^{balazm@saske.sk" class="auth_mail" title="E-mail the corresponding author} ; Erika Dutková ; ^a ; ^{dutkova@saske.sk" class="auth_mail" title="E-mail the corresponding author} ; Peter Balá ; ž^a ; ^{balaz@saske.sk" class="auth_mail" title="E-mail the corresponding author} ; Martin Kello^b ; ^{martin.kello@upjs.sk" class="auth_mail" title="E-mail the corresponding author} ; Gabriela Mojži&scaron ; ová ; ^b ; ^{gabriela.mojzisova@upjs.sk" class="auth_mail" title="E-mail the corresponding author} ; Já ; n Mojži&scaron ; ^b ; ^{jan.mojzis@upjs.sk" class="auth_mail" title="E-mail the corresponding author} ; Má ; ria Vilková ; ^c ; ^{maria.vilkova@upjs.sk" class="auth_mail" title="E-mail the corresponding author} ; Já ; n Imrich^c ; ^{jan.imrich@upjs.sk" class="auth_mail" title="E-mail the corresponding author} ; Miroslav Psotka^c ; ^d ; ^{miroslav.psotka@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Mechanochemistry ; Capping ; CdS/ZnS nanocrystals ; l-cysteine ; Polyvinylpyrrolidone ; Toxicity
• 刊名：Journal of Colloid and Interface Science
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：486
• 期：Complete
• 页码：97-111
• 全文大小：5149 K

文摘

The wet mechanochemical procedure for the capping of the CdS and CdS/ZnS quantum dot nanocrystals is reported. class="smallcaps">l-cysteine and polyvinylpyrrolidone (PVP) were used as capping agents. When using class="smallcaps">l-cysteine, the dissolution of cadmium(II) was almost none for CdS/ZnS nanocrystals. Moreover, prepared CdS- and CdS/ZnS-cysteine nanosuspensions exhibited unimodal particle size distributions with very good stability, which was further supported by the zeta potential measurements. The Fourier-transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopy showed the successful embedment of cysteine into the structure of the nanocrystals. Additionally, the optical properties were examined, and the results showed that the cysteine nanosuspension has promising fluorescence properties. On the other hand, PVP was not determined to be a very suitable capping agent for the present system. In this case, the release of cadmium(II) was higher in comparison to the class="smallcaps">l-cysteine capped samples. The nanosuspensions were successfully used for in vitro studies on selected cancer cell lines. Using fluorescence microscopy, it was evidenced that the nanocrystals enter the cell and that they can serve as imaging agents in biomedical applications.