Molecular characterization of class b carbapenemases in advanced stage of dissemination and emergence of class d carbapenemases in Enterobacteriaceae from Croatia
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- 作者：Branka Bedenića ; b ; branka.bedenic@kbc-zagreb.hr" class="auth_mail" title="E-mail the corresponding author ; Sanda Sardelićc ; sandasard@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Josefa Luxnerd ; josefa.luxner@medunigraz.at" class="auth_mail" title="E-mail the corresponding author ; Zrinka Bo&scaron ; njaka ; b ; zrinkabosnjak@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dijana Varda-Brkićb ; dijanavb098@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Amarela Lukić-Grliće ; amarela.lukic@kdb.hr" class="auth_mail" title="E-mail the corresponding author ; Ivana Marekovića ; b ; imarekov@kbc-zagreb.hr" class="auth_mail" title="E-mail the corresponding author ; Sonja Frančula-Zaninovićf ; Sonja.francula@post.t-com.hr" class="auth_mail" title="E-mail the corresponding author ; Marija Krilanovićg ; marija.krilanovic@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dorotea &Scaron ; ijakh ; dora.peta@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Andrea Grisoldd ; andrea.grisold@medunigraz.at" class="auth_mail" title="E-mail the corresponding author ; Gernot Zarfeld ; gernot.zarfel@medunigraz.at" class="auth_mail" title="E-mail the corresponding author
- 关键词：Enterobacteriaceae ; VIM-1 ; NDM-1 ; OXA-48 ; Carbapenems
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：43
- 期：Complete
- 页码：74-82
- 全文大小：545 K
文摘
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In total 68 carbapenem-resistant isolates were analyzed: 34 Enterobacter cloacae, 18 Citrobacter freundii, 15 Klebsiella pneumoniae and 1 Klebsiella oxytoca
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Sixty-five isolates were found to harbour VIM-1 carbapenemase, seven of which were positive also for NDM-1, while two strains harboured only NDM-1.
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Three different types of carbapenemases were identified showing the complexity of carbapenemase producing Enterobacteriaceae in Croatia.
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Four different plasmid-incompatibility groups were found: A/C, L/M, N and FIIAs.
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K. pneumoniae isolates showed high diversity of rep-PCR patterns in contrast to E. cloacae and C. freundii.