Cardiotoxic effects of the Vipera ammodytes ammodytes venom fractions in the isolated perfused rat heart
详细信息 查看全文
- 作者：Svjetlana Karabuvaa ; svjetlana.karabuva@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ivica Brizićb ; ivicabrizic@net.hr" class="auth_mail" title="E-mail the corresponding author ; Zorica Latinovićc ; d ; zorica.latinovic@ijs.si" class="auth_mail" title="E-mail the corresponding author ; Adrijana Leonardic ; Adrijana.Leonardi@ijs.si" class="auth_mail" title="E-mail the corresponding author ; Igor Križajc ; e ; igor.krizaj@ijs.si" class="auth_mail" title="E-mail the corresponding author ; Boris Luk&scaron ; ića ; f ; boris.luksic1@st.t-com.hr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Snake venom ; Vipera ammodytes ammodytes ; Cardiotoxicity ; Isolated rat heart ; Phospholipase A2
- 刊名：Toxicon
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：98-104
- 全文大小：522 K
文摘
- class="listitem" id="list_ulist0010">
- class="label">•
Cardiotoxic effects of the Vipera a. ammodytes venom were mainly associated with fraction harboring proteins of ∼14 kDa.
- class="label">•
The main cardiotoxic fraction of the venom induced rapid and irreversible asystolia in isolated rat heart.
- class="label">•
This fraction generated also ventricular fibrillation and tachycardia of the isolated rat heart.
- class="label">•
Cardiotoxicity of the venom is likely associated with the venom secreted phospholipases A2.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |