Tight junctions form a barrier in porcine hair follicles
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- 作者：Christiane Mathesa ; 1 ; Johanna M. Brandnerb ; 1 ; brandner@uke.de" class="auth_mail" title="E-mail the corresponding author ; Michael Lauee ; Simon S. Raeschc ; Steffi Hansenc ; Antonio V. Faillad ; Sabine Vidalb ; Ingrid Mollb ; Ulrich F. Schaefera ; Claus-Michael Lehra ; c ; Claus-Michael.Lehr@helmholtz-hzi.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biotin-SH ; EZ-Link&trade ; -Sulfo-NHS-LC-Biotin ; CL ; companion cell layer ; CCL ; central cell layers ; Cldn ; claudin ; EDTA ; ethylenediaminetetraacetic acid ; EM ; electron microscopy ; He* ; differentiated Henle cells of inner root sheath ; HF ; hair follicle ; IRS ; inner root sheath ; NP ; nanoparticle ; Ocln ; occludin ; ORS ; outer root sheath ; PLGA ; poly(lactic-co-glycolic acid) ; SC ; stratum corneum ; TJ ; tight junction ; ZO ; zonula-occludens
- 刊名：European Journal of Cell Biology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：95
- 期：2
- 页码：89-99
- 全文大小：4891 K
文摘
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Porcine hair follicles contain barrier-forming tight junctions (TJs).
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Complex follicular barrier system made of stratum corneum and TJs.
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Follicular TJ barrier can be opened using EDTA.
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Nanoparticles only seen in follicular regions lined with functional tight junctions.
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TJ protein distribution in porcine hair follicle is similar as in human.