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Pain and functional improvement effects of methylene blue injection on the soft tissue around fusion site after traumatic thoracolumbar fixation: A double-blind, randomized placebo-controlled study
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We assessed effects of MB on pain and ODI after traumatic thoracolumbar fixation.

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We analyzed 50 patients who underwent standard posterior pedicular screw fixation.

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A single dose of MB (1 ml at a concentration of 0.5%) reduced postoperative pain.

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MB was associated with a significant improvement in functional QOL.

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No side effects or complications related to the use of MB were observed.

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