Determination of cyclodextrin content using periodate oxidation by capillary electrophoresis

详细信息    查看全文

• 作者：Pumera ; Martin ; Jel&iacute ; nek ; Ivan ; Jindrich ; Jindrich ; Coufal ; Pavel ; Horský ; Jir&iacute
• 关键词：Malaprade’ ; s reaction ; Cyclodextrins ; Carbohydrates ; Periodate ; Acrylamide&ndash ; allylcyclodextrin copolymer ; Polymers
• 刊名：Journal of Chromatography A
• 出版年：2000
• 出版时间：September 1, 2000
• 年：2000
• 卷：891
• 期：1
• 页码：201-206
• 全文大小：95.2 K

文摘

A simple and general method suitable for the determination of cyclodextrin content in various matrices is described. The proposed method involves selective cleavage of C–C bonds with vicinal hydroxyl groups by means of periodate (Malaprade’s reaction). The amount of produced iodate is monitored by capillary electrophoresis. Optimized electrophoretic conditions (20 mM disodium tetraborate with 1 mM tetradecyltrimethylammonium bromide, direct UV detection λ