Vaccine escape in 2013-4 and the hydropathic evolution of glycoproteins of A/H3N2 viruses
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- 作者：J.C. Phillips jcphillips8@comcast.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：Evolution ; Clustering ; Low-dimensional ; Bioinformatics ; Scaling ; Fractal
- 刊名：Physica A: Statistical Mechanics and its Applications
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：455
- 期：Complete
- 页码：38-43
- 全文大小：573 K
文摘
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Vaccine effectiveness depends on selecting the right virus strain as target.
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There are thousands of circulating flu virus strains.
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In 2014 vaccine effectiveness dropped from normal 50% to 15%.
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Hydropathic analysis explains 2014 failure qualitatively and quantitatively.
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The same analysis predicts 2015 vaccine effectiveness will be below 10%.