Glucose homeostasis in rats treated with 4-vinylcyclohexene diepoxide is not worsened by dexamethasone treatment

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• 作者：Francielle Garghetti Battiston^a ; Cristiane dos Santos^a ; Amanda Marreiro Barbosa^a ; Sibele Sehnem^a ; Ellen Cristina Rivas Leonel^b ; Sebastiã ; o Roberto Taboga^b ; Janete A. Anselmo-Franci^c ; Fernanda Barbosa Lima^a ; Alex Rafacho^a ; ^{alex.rafacho@ufsc.br} ; ^{alex.rafacho@ufsc.br} ;
• 关键词：Aging ; Female ; Metabolism ; Ovarian failure ; Senescence ; Steroid hormones
• 刊名：The Journal of Steroid Biochemistry and Molecular Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：165
• 期：part_PB
• 页码：170-181
• 全文大小：3170 K
• 卷排序：165

文摘

4-VCD administered early in life causes ovary hypofunction in adult rats. GC side effects on glucose metabolism are not aggravated by ovarian failure in rats. Ovarian failure is not the sole factor mediating metabolic disturbances during aging.