- 作者：Akihiko Nogami ; Shigeto Naito ; Hiroshi Tada ; Koichi Taniguchi ; Yoshihiro Okamoto ; Shigeyuki Nishimura ; Yasuteru Yamauchi ; Kazutaka Aonuma ; Masahiko Goya ; Yoshito Iesaka ; Michiaki Hiroe
- 关键词：ACC/AHA Clinical Competence Statement ; electrophysiology ; ablation ; cardioversion ; arrhythmia
- 刊名：Journal of the American College of Cardiology
- 出版年：2000
- 出版时间：September 2000
- 年：2000
- 卷：36
- 期：3
- 页码：811-823
- 全文大小：1204 K
The purpose of this study was to determine the relation of diastolic and presystolic potentials recorded during verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) to reentry circuit.
BACKGROUND
Successful ablation of verapamil-sensitive ILVT at the zone of slow conduction from which the diastolic potential is recorded has been reported. However, the relationship between the diastolic potential and the reentrant circuit remains a matter of debate.
METHODS
Radiofrequency (RF) ablation was performed in 20 patients with verapamil-sensitive ILVT. After identifying the ventricular tachycardia (VT) exit site, we searched for the mid-diastolic potential (P1) during VT. Entrainment followed by RF current application was performed. If the mid-diastolic potential could not be detected, RF current was applied at the VT exit site showing the earliest ventricular activation with a single fused presystolic Purkinje potential (P2).
RESULTS
In 15 of 20 patients, both P1 and P2 were recorded during VT from midseptal region. Entrainment pacing captured P1 orthodromically and reset the VT. The interval from stimulus to P1 was prolonged as the pacing rate was increased. Radiofrequency ablation was successfully performed at this site in all 15 patients. After successful ablation, P1 appeared after the QRS complex during sinus rhythm with the identical sequence to that during VT. In the remaining five patients, the diastolic potential could not be detected, and a single fused P2 was recorded only at the VT exit site. Successful ablation was performed at this site in all five patients.
CONCLUSIONS
This study demonstrates that P1 and P2 are critical potentials in a circuit of verapamil-sensitive ILVT and suggests the presence of a macroreentry circuit involving the normal Purkinje system and the abnormal Purkinje tissue with decremental property and verapamil-sensitivity.