Field-evolved resistance to Bt Cry1Ac toxin has developed in Plutella xylostella.
Proteomics was used to identify midgut proteins may relate to Cry1Ac resistance.
Thirty-one expression-altered proteins in susceptible and resistant strains were detected.
Five Cry1Ac-binding proteins were identified in Cry1Ac-susceptible P. xylostella.
Diverse midgut proteins may be associated with Cry1Ac resistance in P. xylostella.
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