A novel approach towards dethioacetalization reactions with H₂O₂¨CSOCl₂ system

详细信息    查看全文

• 作者：Kiumars  ; Bahrami^a ;   ; ^b ;   ; ^{kbahrami2@hotmail.com} ; Mohammad Mehdi  ; Khodaei^a ;   ; ^b ;   ; ; Maryam  ; Tajik^a ; Vida  ; Shakibaian^a
• 关键词：Deprotection ; Carbonyl protecting group ; Dethioacetalization ; Dithioacetals ; Hydrogen peroxide
• 刊名：Chinese Chemical Letters
• 出版年：2012
• 出版时间：January 2012
• 年：2012
• 卷：23
• 期：1
• 页码：81-85
• 全文大小：1193 K

文摘

A simple and efficient protocol for the deprotection of dithioacetal, 1,3-dithianes and 1,3-dithiolanes has been developed using H₂O₂¨CSOCl₂ reagent system. In addition to the absence of overoxidation products for oxidation-prone substrates, high chemoselectivity, the low cost and availability of the reagents, simplicity of the method, short reaction times, and excellent yields can also be considered as strong points for this method.