An integrated genomic and proteomic approach to identify signatures of endosulfan exposure in hepatocellular carcinoma cells
详细信息 查看全文
- 作者：Deepa Gandhia ; Prashant Taralea ; Pravin K. Naogharea ; Amit Bafanaa ; Kannan Krishnamurthia ; Patrizio Arrigob ; Sivanesan Saravanadevia ; ss_devi@neeri.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：ACIN1 ; apoptotic chromatin condensation inducer 1 isoform 1 ; ARNT2 ; aryl-hydrocarbon receptor nuclear translocator 2 ; CYP8B1 ; cytochrome P450 family 8 subfamily B polypeptide ; H2BFWT ; histone H1.2 ; H2B histone family member W ; testis-specific (T) ; HIST2H4A ; histone cluster 2 ; H4a ; NFAT5 ; nuclear factor of activated T-cells 5 ; PHLDA1 ; pleckstrin homology-like domain family A member 1 ; PLAA ; phospholipase A2-activating protein ; PAX1 ; paired box 1 ; PRDX3 ; peroxiredoxin ; NRAP ; nebulin-related anchor
- 刊名：Pesticide Biochemistry and Physiology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：125
- 期：Complete
- 页码：8-16
- 全文大小：796 K
文摘
- •
Persistence of endosulfan around the globe is a matter of great concern.
- •
Integrated “omics” approach is applied to identify molecular fingerprints.
- •
Genomic and proteomic signatures in endosulfan exposed hepatic cells are reported.
- •
This will help in developing specific biomarkers for endosulfan exposure.