A novel method, co-solution, coprecipitation and dehydrated ethanol treatment is employed for n-HA/PPC biomaterial.

PEG6000 was modified on n-HA surface to create chemical bondings between the inorganic mineral and organic polymer.

n-HA is distributed evenly in the PPC matrix, and good interface bonding between n-HA and PPC is observed.

The in vivo test confirms that the n-HA/PPC composite is biocompatible and shows no negative effect on osteoblasts.