Constituents of various wood-rotting basidiomycetes

详细信息    查看全文

• 作者：Rö ; secke ; Joachim ; Kö ; nig ; Wilfried A.
• 关键词：Fomitopsis pinicola ; Ganoderma lipsiense ; Fomes fomentarius ; Gloeophyllum odoratum ; Polyporaceae ; Basidiomycetes ; Crust ; Triterpenes ; Steroids ; Aromatic compounds
• 刊名：Phytochemistry
• 出版年：2000
• 出版时间：July 1, 2000
• 年：2000
• 卷：54
• 期：6
• 页码：603-610
• 全文大小：233 K

文摘

Phytochemical investigation of n-hexane and methanol extracts of fruiting bodies of the wood-rotting fungi Fomitopsis pinicola, Ganoderma lipsiense, Fomes fomentarius and Gloeophyllum odoratum led to the isolation and identification of several triterpene derivatives and some aromatic compounds derived from lignin. These are the new natural products, namely, pinicolic acid E (16α-hydroxy-3-oxolanosta-8,24-dien-21-oic acid) and pinicolol C (3-oxolanosta-7,9(11),24-trien-15α,21-diol) from the crust of F. pinicola, ganoderenic acid D {(E)-7β-hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-dien-26-oic acid} and ganoderic acid N (7β,20-dihydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid) from G. lipsiense and ergosterol peroxide (5α,8α-epi-dioxyergost-6-en-3β-ol) as well as ergost-7-en-3-one from F. fomentarius. From G. odoratum, dehydroeburicoic acid {24- methylene-3-oxolanosta-7,9(11)-dien-21-oic acid}, the dimethylacetal of 4,4,14α-trimethyl-24-oxo-5α-chol-8-en-21-oic acid and some aromatic compounds, of which 1-(4′-methoxyphenyl)-1,2-ethandiol is a new natural product, were isolated. Furthermore, a complete set of ¹³C NMR data of the steryl esters 3β-linoleyloxyergosta-7,24(28)-diene, 3β-linoleyloxyergosta-7,22-diene and 3β-linoleyloxyergost-7-ene, which could be identified as a mixture in all investigated fungi, could be recorded. It was proved by HPLC and TLC investigations, that the crust on top of the fruiting bodies of F. pinicola consists of lanostane derivatives.