Metabolic engineering of cyanobacteria for the photosynthetic production of succinate
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- 作者：Ethan I. Lan ; ethanilan@nctu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; Crystal T. Wei
- 关键词：Cyanobacteria ; Succinic acid ; Carbon dioxide re-utilization ; Bio-based production
- 刊名：Metabolic Engineering
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：483-493
- 全文大小：1526 K
文摘
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Heterologous α-ketoglutarate decarboxylase and succinate semialdehyde dehydrogenase were expressed in S. elongatus PCC 7942.
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Expression of PEP carboxylase rescued growth retardation caused by introduction of succinate production pathway.
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Succinate secretion increased with pH of culture medium.
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430 mg/L of succinate was produced under photosynthetic conditions.