Dynamic MR Spectroscopy of brain metabolism using a non-conventional spectral averaging scheme

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• 作者：Abdul Nashirudeen Mumuni ; ¹ ; ^{mnashiru@uds.edu.gh} ; John McLean ^{johnmclean@nhs.net}
• 关键词：AP ; anterior-posterior direction ; Bo ; field strength ; BOLD ; blood oxygen level dependent ; CHESS ; CHEmical Shift Selective preparation ; Cho ; Choline ; Cr ; Creatine ; FID ; free induction decay ; fMRI ; functional magnetic resonance imaging ; fMRS ; functional magnetic resonance spectroscopy ; FOV ; field-of-view ; GE ; General Electric ; Gln ; glutamine ; Glu ; glutamate ; mI ; myo-inositol ; MR ; magnetic resonance ; MRI ; magnetic resonance imaging ; MRS ; magnetic resonance spectroscopy ; NAA ; N-acetyl aspartate ; NEX
• 刊名：Journal of Neuroscience Methods
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：277
• 期：Complete
• 页码：113-121
• 全文大小：1841 K
• 卷排序：277

文摘

Standard functional MRS acquisition may be susceptible to movement artefacts. Averaging of two spectral lines in steps of 6 s was therefore implemented. Higher BOLD changes were observed in single paradigm compared to block paradigm. BOLD changes in the block paradigm were generally lower than reported averages. Temporal resolution of two averaged lines thus reduces recorded BOLD effects.