Danhong injection attenuates cardiac injury induced by ischemic and reperfused neuronal cells through regulating arginine vasopressin expression and secretion
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- 作者：Mingzhu Yanga ; b ; John Orgaha ; b ; Jie Zhua ; b ; Guanwei Fana ; Jihong Hand ; Xiaoying Wanga ; b ; e ; Boli Zhanga ; Yan Zhua ; b ; c ; yanzhu.harvard@iCloud.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AVP ; arginine vasopressin ; CK ; creatine kinase ; DHI ; danhong injection ; FBS ; fetal bovine serum ; IR ; ischemic reperfusion ; LDH ; lactate dehydrogenase ; OGD ; oxygen-glucose deprivation ; PRNCs ; primary rat neuronal cells ; PS ; penicillin-streptomycin ; PI ; propidium iodide ; RCMs ; primary rat cardiac myocytes
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：1642
- 期：Complete
- 页码：516-523
- 全文大小：7911 K
文摘
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Supernatant from ischemic and reperfusion neurons induces myocytes injury.
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Arginine vasopressin in ischemic and reperfusion neurons increases significantly.
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Over dose of arginine vasopressin causes myocytes damage.
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Danhong injection down-regulates arginine vasopressin in neurons.
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Danhong injection attenuates myocytes injury induced by arginine vasopressin.