Electrospun biocompatible Chitosan/MIL-101 (Fe) composite nanofibers for solid-phase extraction of ^Δ9-tetrahydrocannabinol in whole blood samples using Box-Behnken experimental design

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• 作者：Mina Asiabi^a ; Ali Mehdinia^b ; ^{mehdinia@inio.ac.ir} ; Ali Jabbari^a
• 关键词：Electrospining ; Chitosan/MIL-101 (Fe) ; Biocompatible composite nanofibers ; Δ9-Tetrahydrocannabinol ; Central composite design
• 刊名：Journal of Chromatography A
• 出版年：2017
• 出版时间：6 January 2017
• 年：2017
• 卷：1479
• 期：Complete
• 页码：71-80
• 全文大小：2471 K
• 卷排序：1479

文摘

Novel Electrospun Biocompatible Chitosan/MIL-101 (Fe) Composite was synthesized. The composite Nanofibrous mat was used as adsorbent for solid-phase extraction. A Box-Behnken design was used for optimization of the experiment parameters. The method was successfully applied in determination of THC in Whole blood samples. The method features low LOD, wide dynamic range, and good accuracy and precision.