Darwin Comes to Clinic
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- 作者：Arthur L. Beaudet1 ; abeaudet@bcm.edu
- 刊名：Trends in Genetics
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：33
- 期：1
- 页码：1-2
- 全文大小：867 K
- 卷排序：33
文摘
What might be the benefits of whole-genome rather than whole-exome sequencing (WES) for identifying the genetic causes of human disabilities? A recent paper by Doan et al. focuses attention on mutations in human accelerated regions (HARs), a subset of genomic regulatory elements showing accelerated evolution between chimpanzees and humans.