Management of the pregnant mare and long-term consequences on the offspring

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• 作者：Pauline Peugnet^a ; ^{peugnetpauline@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Morgane Robles^a ; Laurence Wimel^b ; Anne Tarrade^a ; Pascale Chavatte-Palmer^a
• 关键词：Equids ; Developmental origins of health and disease ; Embryo transfer ; Nutrition ; Placenta
• 刊名：Theriogenology
• 出版年：2016
• 出版时间：1 July 2016
• 年：2016
• 卷：86
• 期：1
• 页码：99-109
• 全文大小：503 K

文摘

The study of early developmental conditioning of health and disease in adulthood is particularly relevant in the horse, which is bred mainly to perform in demanding sport challenges. On the basis of this concept, the management of the broodmare could be considered an effective means to produce animals with the desired features. Knowledge on the Developmental Origins of Health and Disease in the equine species remains relatively scarce, with some experimental studies and one single epidemiologic study. Data highlight the determinant role of the maternal environment for postnatal body conformation, immune response, energy homeostasis, osteoarticular status and thyroidal, adrenocortical, and cardiovascular functions of the foal. Most research, however, focuses on the first months/years after birth. Long-term effects on the adult horse phenotype have not been investigated so far.