Early-life experiences and the development of adult diseases with a focus on mental illness: The Human Birth Theory

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• 作者：Stefania Maccari^a ; ^f ; ^g ; ^&dagger ; ; ^{stefania.maccari@univ-lille1.fr} ; Daniela Polese^b ; ^c ; ^&dagger ; ; Marie-Line Reynaert^a ; Tiziana Amici^d ; Sara Morley-Fletcher^a ; Francesca Fagioli^e
• 关键词：CNS ; central nervous system ; DOHaD ; developmental origins of health and disease ; EEG ; electroencephalography ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal ; IGF ; insulin/insulin-like growth factor ; PRS ; perinatal stress ; SATs ; Spontaneous Activity Transients
• 刊名：Neuroscience
• 出版年：2017
• 出版时间：7 February 2017
• 年：2017
• 卷：342
• 期：Complete
• 页码：232-251
• 全文大小：2172 K
• 卷排序：342

文摘

Prenatal stress induces reduced maternal care during the postnatal development of the offspring. Postnatal adoption, which improves maternal care, corrects the effects of prenatal stress. In the human species, negative postnatal factors might occur and determine mental diseases. Newborns are equal at the time of birth and mental illness occurs afterwards. The concept of the Human Birth Theory leads to a comprehension of mental illness.