Involvement of endothelium in the vasorelaxant effects of 3,4-DHPEA-EA and 3,4-DHPEA-EDA, two major functional bioactives in olive oil
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- 作者：Marí ; a Segadea ; Roberto Bermejoa ; Aní ; bal Silvab ; Fá ; tima Paiva-Martinsb ; José ; Gil-Longoa ; 1 ; Manuel Campos-Toimila ; 1 ; manuel.campos@usc.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：[Ca2+]c ; cytosolic Ca2+ concentration ; DAF-2 ; 4 ; 5-diaminofluorescein ; DAF-2-DA ; 4 ; 5-diaminofluorescein diacetate ; DMSO ; dimethyl sulphoxide ; ECGS ; endothelial cell growth supplement ; eNOS ; endothelial NO synthase ; FBS ; foetal bovine serum ; fluo-4 AM ; fluo-4 acetoxymethyl ester ; HUVEC ; human umbilical vein endothelial cells ; KBS ; Krebs bicarbonate solution ; L-NA ; NG-nitro-L-arginine ; NAC ; N-acetylcysteine ; OOPP ; olive oil polyphenols ; ROS ; reactive oxygen species
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：23
- 期：Complete
- 页码：637-646
- 全文大小：667 K
文摘
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3,4-DHPEA-EA and 3,4-DHPEA-EDA olive oil polyphenols induce vascular relaxation.
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5">These polyphenols may be important for preventing hypertension.
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It is possible to develop functional foods enriched with these functional bioactives.