用户名: 密码: 验证码:
Preliminary results of a prospective multicentric French study of PDR 3D brachytherapy for cervix carcinoma
详细信息    查看全文
文摘
Brachytherapy is a fundamental step in the treatment of patients with cervical cancer. Brachytherapy allows a significant increase in the local control rate as well as the survival rate, Brachytherapy has to be performed as soon as possible after external irradiation in order to maintain the overall treatment time below 53 days. Technical and dosimetric data characterizing low dose-rate brachytherapy using ICRU 38 recommendations have led to an improvement in local control and a decrease in complications. Data are less well known for other dose rates. The role of interstitial brachytherapy is not clearly defined and its potential benefit is probably balanced by an increase in severe complications. Concomitant brachy-chemotherapy requires further clinical investigations, even if concomitant radio-chemotherapy has become a standard in advanced cervical cancers.

ass=""h3"">Résumé

La curiethérapie est une étape fondamentale dans le traitement des patientes atteintes de cancer du col de l'utérus. Elle permet une augmentation significative des taux de contrôle local et de survie. Saalisation doit se situer le plus près possible de la fin de la radiothérapie externe, en cas d'irradiation exclusive, de façon à ne pas augmenter l'étalement au-delà de 53 jours. Les données techniques et dosimétriques caractérisant la curiethérapie de bas débit de dose et exprimées généralement à l'aide des recommandations de l'ICRU 38 ont permis d'augmenter le taux de contrôle local et de diminuer celui de complications. Ces données sont moins bien connues pour les autres types de débit. La place de la curiethérapie interstitielle reste mal définie dans les formes étendues et son bénéfice potentiel se fait vraisemblablement au prix d'une élévation du taux des complications. L'intéra;t de la chimiocuriethérapie nécessite des investigations cliniques complémentaires, ma;me si la chimioradiothérapie est devenue un standard dans les stades de pronostic défavorable.

<a href=""http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VR6-4465WS1-6Y-1&_cdi=6226&_user=10&_orig=article&_coverDate=04 % 2F30 % 2F2000&_sk=999959997&view=c&wchp=dGLbVlW-zSkWA&md5=a8d7885dcffae52f62ba0fa013f009dc&ie=/sdarticle.pdf"">ame=""pdf"" style=""vertical-align:absmiddle;"" border=""0"" src=""http://www.sciencedirect.com/scidirimg/icon_pdf.gif"" alt=""""> Purchase PDF (762 K)a>able>
ashed #CCCCCC; border-bottom: 1px solid #CCCCCC;background-color: #F6F6F6"" width=340>able cellpadding=0 cellspacing=0 width=""100 % "">align=""top"" style=""padding:3px 5px 0px 5px"">ang.gif"" alt=""""><a href=""/science?_ob=RelatedArtURL&_udi=B6X3G-4S86YJ8-R&_orig=article&_acct=C000050221&_version=1&_userid=10&md5=25039e2e390d936994c236284093a870"">View More Related Articlesa>able>ass=""nojs"">argin: 0px; text-align: center"" onclick=""toggleMLKT('B6X3G-4S86YJ8-R','/scidirimg/btn_arrow_up_off.gif','/scidirimg/btn_arrow_down_off.gif','http://www.sciencedirect.com/science')"">arrow_up_off.gif"" id=""mlktArrow"" alt="""" border=""0"" onmouseover=""mlktHover(1,'/scidirimg/sci_dir/')"" onmouseout=""mlktHover(0,'/scidirimg/')"">able> align=""right"">
abBoxContent"">
able>
articleBody"" class=""font3"">
ass=""articleHeaderInner"" id=""articleHeader"">ar.gif"" width=""1"" height=""10"" border=""0"" alt=""""><a href=""http://dx.doi.org/10.1016/j.brachy.2008.02.347"" target=""doilink"" onClick=""var doiWin; doiWin=window.open('http://dx.doi.org/10.1016/j.brachy.2008.02.347','doilink','scrollbars=yes,resizable=yes,directories=yes,toolbar=yes,menubar=yes,status=yes'); doiWin.focus()"">doi:10.1016/j.brachy.2008.02.347a> <a href = ""/science?_ob=HelpURL&_file=doi.htm&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a143a86ddc585c54adbe80b2046626c3"" target=""sdhelp"" onMouseOver = ""window.status='Help is Available';return true"" onClick=""var helpWin; helpWin=window.open('/science?_ob=HelpURL&_file=doi.htm&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a143a86ddc585c54adbe80b2046626c3','sdhelp','scrollbars=yes,resizable=yes,directories=no,toolbar=no,menubar=no,status=no,width=760,height=570'); helpWin.focus()"">alt=""How to Cite or Link Using DOI (Opens New Window)"" title=""How to Cite or Link Using DOI (Opens New Window)"" border=""0"" align=""absmiddle"">a>
Copyright &#xa9; 2008 American Brachytherapy Society Published by Elsevier Inc.
ass=""articleTitle"">

Preliminary results of a prospective multicentric French study of PDR 3D brachytherapy for cervix carcinoma

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700