Full spectrum and selected spectrum based chemometric methods for the simultaneous determination of Cinnarizine and Dimenhydrinate in laboratory prepared mixtures and pharmaceutical dosage form

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• 作者：Shereen M. Tawakkol^a ; Mohamed B. El-Zeiny^b ; ^{mohamedbadrelzeiny@gmail.com} ; A. Hemdan^c
• 关键词：Cinnarizine ; Dimenhydrinate ; Genetic algorithm ; SRACLS ; CRACLS ; PLS
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：173
• 期：Complete
• 页码：892-896
• 全文大小：467 K
• 卷排序：173

文摘

Different multivariate models for the analysis of CNN and DMN Can be applied for severely overlapped and complex binary mixtures GA introduced less complex models. Can be applied for analysis of the dosage form with no inference of excipients