Analyses of differentially expressed genes after exposure to acute stress, acute ethanol, or a combination of both in mice

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• 作者：Jessica A. Baker^a ; Jingxin Li^b ; Diana Zhou^a ; Ming Yang^c ; Melloni N. Cook^d ; Byron C. Jones^e ; Megan K. Mulligan^e ; Kristin M. Hamre^a ; ¹ ; ^{khamre@uthsc.edu} ; Lu Lu^e ; ^f ; ¹ ; ^{lulu@uthsc.edu}
• 关键词：Ethanol ; Stress ; Gene expression ; Hippocampus ; Bioinformatic analysis
• 刊名：Alcohol
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：58
• 期：Complete
• 页码：139-151
• 全文大小：2323 K
• 卷排序：58

文摘

Exposure to stress, ethanol, or both results in distinct changes in gene expression. There are specific changes in gene expression that differ between the combined treatment group and the ethanol-only group. Alcohol- and stress-related phenotypes correlated with majority genes. Identification of relevant Ptp4a1 network may mediate ethanol/stress interactions.