There were 9865 patients (40.6% women) who underwent CEA (n聽= 6492) and CAS (n聽= 3373). The primary end point was a composite of death, stroke, and myocardial infarction at 30聽days.
There was no difference in age and ethnicity between genders, but men were more likely to be symptomatic (41.6% vs 38.6%; P聽< .003). There was a higher prevalence of hypertension and chronic obstructive pulmonary disease in women, whereas men had a higher prevalence of coronary artery disease, history of myocardial infarction, and smoking history. For disease etiology in CAS, restenosis was more common in women (28.7% vs 19.7%; P聽< .0001), and radiation was higher in men (6.2% vs 2.6%; P聽< .0001). Comparing by gender, there were no statistically significant differences in the primary end point for CEA (women, 4.07%; men, 4.06%) or CAS (women, 6.69%; men, 6.80%). There remains no difference after stratification by symptomatology and multivariate risk adjustment.
In this large, real-world analysis, women and men demonstrated similar results after CEA or CAS. These data suggest that, contrary to previous reports, women do not have a higher risk of adverse events after carotid revascularization.