A method of UHPLC-QTOF-MS was developed for analysis of Yin-Qiao-Jie-Du tablets.
A good separation was achieved within 30 min and 41 major peaks were obtained.
31 of constituents were identified according to obtained MS data and retention time.
Contents of 21 ingredients from18 batches of YQJD tablets were applied for OPLS-DA.
OPLS-DA was successfully used for assessing the quality consistency and stability.