Enhancement of docosahexaenoic acid synthesis by manipulation of antioxidant capacity and prevention of oxidative damage in Schizochytrium sp.
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- 作者：Lu-Jing Ren1 ; Xiao-Man Sun1 ; Xiao-Jun Ji ; Sheng-Lan Chen ; Dong-Sheng Guo ; He Huang ; biotech@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Schizochytrium sp. ; Docosahexaenoic acid ; Reactive oxygen species ; Total antioxidant capacity
- 刊名：Bioresource Technology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：223
- 期：Complete
- 页码：141-148
- 全文大小：1969 K
文摘
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A new control strategy by manipulating antioxidant capacity was proposed.
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Ascorbic acid enhances cellular antioxidant capacity to resist oxidative injury.
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ROS decreased by 35.5% and T-AOC kept above zero until the end of fermentation.
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Ascorbic acid increased PUFA content with specificity improvement in DHA content.
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DHA yield was increased by 44% by two-point ascorbic acid addition strategy.