SERS characterization of neuropeptide Y and its C-terminal fragments deposited onto colloidal gold nanoparticle surface

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• 作者：Helena Domin^a ; Natalia Piergies^b ; Dominika Święch^c ; Ewa Pięta^b ; Edyta Proniewicz^c ; ^{proniewi@agh.edu.pl}
• 关键词：Surface-enhanced Raman spectroscopy (SERS) ; Colloidal gold nanoparticles ; SERS spectra ; Neuropeptide Y ; Y2 receptor agonist ; C-terminal NPY fragments
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：149
• 期：Complete
• 页码：80-88
• 全文大小：1878 K
• 卷排序：149

文摘

SERS was used to investigate NPY and its C-terminal fragments in an aqueous gold sol. The length of the peptide and the solution pH affect the adsorption mode. The tyrosine ring in three forms; i.e., TyrOH, TyrO−, and Tyr*, binds to gold.