Trends in Receipt of Intensive Procedures at the End of Life Among Patients Treated With Maintenance Dialysis

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• 作者：Nwamaka D. Eneanya ; MD ; MPH¹ ; ^{aeneanya@partners.org} ; Susan M. Hailpern ; DrPH ; MS² ; Ann M. O'Hare ; MD ; MA² ; ³ ; ⁴ ; Manjula Kurella Tamura ; MD ; MPH⁵ ; Ronit Katz ; DPhil² ; William Kreuter ; MPA² ; Maria E. Montez-Rath ; PhD⁶ ; Paul L. Hebert ; PhD⁷ ; Yoshio N. Hall ; MD ; MS²
• 关键词：End-of-life ; dialysis ; intensive procedures ; end-stage renal disease (ESRD) ; Hispanic ; elderly ; age differences ; ethnic disparities ; Medicare spending ; health care costs ; hospitalization ; mortality follow-back
• 刊名：American Journal of Kidney Diseases
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：69
• 期：1
• 页码：60-68
• 全文大小：410 K
• 卷排序：69

文摘

Many dialysis patients receive intensive procedures intended to prolong life at the very end of life. However, little is known about trends over time in the use of these procedures. We describe temporal trends in receipt of inpatient intensive procedures during the last 6 months of life among patients treated with maintenance dialysis.Study DesignMortality follow-back study.Setting & Participants649,607 adult Medicare beneficiaries on maintenance dialysis therapy who died in 2000 to 2012.PredictorsPeriod of death (2000-2003, 2004-2008, or 2009-2012), age at time of death (18-59, 60-64, 65-69, 70-74, 75-79, 80-84, and ≥85 years), and race/ethnicity (Hispanic, non-Hispanic black, or non-Hispanic white).OutcomeReceipt of an inpatient intensive procedure (defined as invasive mechanical ventilation/intubation, tracheostomy, gastrostomy/jejunostomy tube insertion, enteral or parenteral nutrition, or cardiopulmonary resuscitation) during the last 6 months of life.ResultsOverall, 34% of cohort patients received an intensive procedure in the last 6 months of life, increasing from 29% in 2000 to 36% in 2012 (with 2000-2003 as the referent category; adjusted risk ratios [RRs] were 1.06 [95% CI, 1.05-1.07] and 1.10 [95% CI, 1.09-1.12] for 2004-2008 and 2009-2012, respectively). Use of intensive procedures increased more markedly over time in younger versus older patients (comparing 2009-2012 to 2000-2003, adjusted RR was 1.18 [95% CI, 1.15-1.20] for the youngest age group as opposed to 1.00 [95% CI, 0.96-1.04] for the oldest group). Comparing 2009 to 2012 to 2000 to 2003, the use of intensive procedures increased more dramatically for Hispanic patients than for non-Hispanic black or non-Hispanic white patients (adjusted RRs of 1.18 [95% CI, 1.14-1.22], 1.09 [95% CI, 1.07-1.11], and 1.10 [95% CI, 1.08-1.12], respectively).LimitationsData sources do not provide insight into reasons for observed trends in the use of intensive procedures.ConclusionsAmong patients treated with maintenance dialysis, there is a trend toward more frequent use of intensive procedures at the end of life, especially in younger patients and those of Hispanic ethnicity.