Silencing Drp1 inhibits glioma cells proliferation and invasion by RHOA/ ROCK1 pathway
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- 作者：Maojia Yina ; 1 ; Qin Lub ; 1 ; Xi Liua ; Teng Wanga ; Ying Liua ; Lifen Chena ; lifen_chen@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glioma ; DRP1 ; RHOA ; ROCK1
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：16 September 2016
- 年：2016
- 卷：478
- 期：2
- 页码：663-668
- 全文大小：2533 K
文摘
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DPR1 is significantly increased in glioma tissues.
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Down-regulation of DRP1 in glioma cells inhibits cell proliferation.
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Down-regulation of DRP1 in glioma cells inhibits cell invasion and induces F-actin remodeling.
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Down-regulation of DRP1 inhibits RHOA/ROCK1 pathway in glioma cells.