Left Ventricular Mechanics in Idiopathic Dilated Cardiomyopathy: Systolic-Diastolic Coupling and Torsion

详细信息    查看全文

• 作者：Jaroslav Meluzin ; MD ; PhD ; FESC ; ^{jaroslav.meluzin@fnusa.cz} ; Lenka Spinarova ; MD ; PhD ; FESC ; Petr Hude ; MD ; Jan Krejci ; MD ; Hana Poloczkova ; MD ; Helena Podrouzkova ; MD ; Martin Pesl ; MD ; Marek Orban ; MD ; Ladislav Dusek ; MD ; PhD ; Josef Korinek ; MD ; PhD
• 关键词：Left ventricular rotation ; Torsion ; Two-dimensional strain echocardiography
• 刊名：Journal of the American Society of Echocardiography
• 出版年：2009
• 出版时间：May 2009
• 年：2009
• 卷：22
• 期：5
• 页码：486-493
• 全文大小：1979 K

文摘

| Figures/TablesFigures/Tables | ReferencesReferences

Background

In idiopathic dilated cardiomyopathy (IDC), myocardial deformational parameters and their mutual relationships remain incompletely characterized.

Methods

Thirty-seven patients with IDC underwent two-dimensional speckle-tracking echocardiography (2D-STE) to assess left ventricular rotation, torsion, and longitudinal, circumferential, and radial systolic and diastolic strains and strain rates. Additionally, 2D-STE was performed in 14 controls.

Results

All deformational parameters on 2D-STE were significantly lower in patients with IDC compared with controls. Seven patients exhibited opposite basal (positive, counterclockwise) and 11 patients exhibited opposite apical (negative, clockwise) rotation at end-systole. Circumferential, radial, and longitudinal early diastolic strain rates were correlated most strongly with the corresponding spatial components of systolic deformation.

Conclusion

In patients IDC, all torsional, systolic, and diastolic deformational parameters were decreased. Corresponding three-dimensional components of systolic and diastolic deformations were closely coupled. Considerable variation in the direction of basal and apical rotation exists in a subset of patients with IDC.