Central poststroke pain: A population-based study

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• 作者：Henriette Klit^a ; Nanna Brix Finnerup^a ; ^{finnerup@ki.au.dk} ; Grethe Andersen^b ; Troels Staehelin Jensen^a ; ^b
• 关键词：Neuropathic pain ; Central pain ; Stroke ; Allodynia ; Hyperalgesia ; Classification
• 刊名：Pain
• 出版年：2011
• 出版时间：April 2011
• 年：2011
• 卷：152
• 期：4
• 页码：818-824
• 全文大小：606 K

文摘

Central poststroke pain (CPSP) is a specific pain condition arising as a direct consequence of a cerebrovascular lesion. There is limited knowledge about the epidemiology and clinical characteristics of this often neglected but important consequence of stroke. In this population-based study, a questionnaire was sent out to all (n = 964) stroke patients identified through the Danish National Indicator Project Stroke Database in Aarhus County, Denmark, between March 2004 and February 2005. All surviving patients who fulfilled 4 questionnaire criteria for possible CPSP (n = 51) were selected for further clinical examination, and their pain was classified by using stringent and well-defined criteria and a detailed, standardized clinical examination. The minimum prevalence of definite or probable CPSP in this population is 7.3 % and the prevalence of CPSP-like dysesthesia or pain is 8.6 % . Pinprick hyperalgesia was present in 57 % , cold allodynia in 40 % , and brush-evoked dysesthesia in 51 % of patients with CPSP. Because of its negative impact on quality of life and rehabilitation, pain is an important symptom to assess in stroke survivors.

In a population-based study, central pain was seen in 7.3 % of stroke survivors and was often associated with hypersensitivity for touch, cold, and pinprick.