Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism
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- 作者：Adam R. Wendea ; d ; Martin E. Youngb ; d ; John Chathama ; d ; Jianhua Zhanga ; d ; Namakkal S. Rajasekarana ; d ; Victor M. Darley-Usmara ; c ; d ; vdarleyusmar@uabmc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：ARE ; antioxidant response element ; ATP ; adenosine triphosphate ; 5-hmC ; hydroxymethylcytosine ; ATG ; AuTophaGy related ; BNIP ; Bcl-2/adenovirus E18 19-kDa-interacting protein ; Drp1 ; dynamin related protein 1 ; EpRE ; electrophile response element ; eNOS ; endothelial cell ; nitric oxide synthase 3 ; G6PD ; Glucose-6-phosphate dehydrogenase ; GCLC/GCLM ; Glutamate cysteine ligase ; GCS ; glutamylcysteine synthetase ; GPX1 ; Glutathione peroxidase 1 ; GSR ; glutathione-reductase ; GTN ; nitroglycerin ; HO-1 ; heme oxyg
- 刊名：Free Radical Biology and Medicine
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：100
- 期：Complete
- 页码：94-107
- 全文大小：2474 K
文摘
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Cellular Bioenergetics represents an integrated metabolic program.
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Integration is mediated through epigenetics, autophagy and the Keap1/Nrf2 pathway.
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Post-translational modification by O-GlcNAc modulates metabolic responses to stress.
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Circadian control of metabolism is a critical element in maintaining physiological metabolism.