Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo

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• 作者：Susanne M. Henning^a ; Paula H. Summanen^b ; ^{carlsonph@aol.com} ; Ru-Po Lee^a ; Jieping Yang^a ; Sydney M. Finegold^b ; ^c ; ^d ; David Heber^a ; Zhaoping Li^a ; ^b ; ^d
• 关键词：Akkermansia muciniphila ; Ellagic acid ; Ellagitannins ; Intestinal bacteria ; Pomegranate extract ; Prebiotic ; Urolithin A
• 刊名：Anaerobe
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：Complete
• 页码：56-60
• 全文大小：433 K
• 卷排序：43

文摘

Pomegranate extract stimulates the growth of Akkermansia muciniphila in vivo. A. muciniphila produces ellagic acid from pomegranate extract ellagitannins. A. muciniphila hydrolyses ellagic acid to metabolites other than urolithin A. A. muciniphila plays a role in the breakdown of phenolic compounds in the intestine. A. muciniphila contributes to the prebiotic effect of pomegranate extract.