Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function
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- 作者：Amy Guimarã ; es-Younga ; Traci Neffb ; Adam J. Dupuya ; Michael J. Goodhearta ; b ; michael-goodheart@uiowa.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endometrial glands ; Development ; Adenogenesis ; Uterus ; Mouse model ; Sox17
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：414
- 期：2
- 页码：219-227
- 全文大小：1080 K
文摘
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Multi-compartment uterine Sox17 deletion impairs normal uterine function.
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Non-epithelial, Sox17-positive stromal cells are necessary for gland formation.
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Mice with Sox17-negative glandular cells are unable to reproduce.