Small HDL subclasses become cholesterol-poor during postprandial period after a fat diet intake in subjects with high triglyceridemia increases

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• 作者：Armando Quintanilla-Cant&uacute ; ^a ; Paola Peñ ; a-de-la-Sancha^a ; Cristobal Flores-Castillo^a ; Ana Mar&iacute ; a Mej&iacute ; a-Dom&iacute ; nguez^b ; Rosalinda Posadas-S&aacute ; nchez^c ; Nonanzit P&eacute ; rez-Hern&aacute ; ndez^a ; Roc&iacute ; o Bautista-P&eacute ; rez^a ; Reyna Esmeralda Enriquez-Calder&oacute ; n^d ; Marco Antonio Ju&aacute ; rez-Oropeza^e ; Jos&eacute ; Manuel Fragoso^a ; Gilberto Vargas-Alarc&oacute ; n^a ; Oscar P&eacute ; rez-M&eacute ; ndez^a ; ^{opmendez@yahoo.com}
• 关键词：Lipoprotein metabolism ; Metabolic syndrome ; Hypertriglyceridemia ; HDL subclasses ; Coronary heart disease ; Hypoalphalipoproteinemia ; Postprandial state
• 刊名：Clinica Chimica Acta
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：464
• 期：Complete
• 页码：98-105
• 全文大小：522 K
• 卷排序：464

文摘

High postprandial triglyceridemia shifts HDL size distribution towards large particles. Triglycerides of large HDL increased at 4 h and remained elevated up to 8 h after meal intake in MS patients. HDL3 subclasses became cholesterol-poor during postprandial state in subjects with high incremental area under the curve (iAUC) of TAG. Postprandial hypertriglyceridemia contributes to structural changes of HDL and hypoalphalipoproteinemia.