Positively charged polymers modulate the fate of human mesenchymal stromal cells via ephrinB2/EphB4 signaling
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- 作者：Ilenia De Lucaa ; 1 ; Anna Di Sallea ; 1 ; Nicola Alessiob ; Sabrina Margaruccia ; Michele Simeonec ; Umberto Galderisib ; Anna Calarcoa ; anna.calarco@ibbr.cnr.it" class="auth_mail" title="E-mail the corresponding author ; Gianfranco Pelusoa
- 关键词：Cationic polymers ; MSCs differentiation ; Cell-cell ephrinB2/EphB4 signaling ; Regenerative medicine
- 刊名：Stem Cell Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：17
- 期：2
- 页码：248-255
- 全文大小：877 K
文摘
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Biomaterials controlling the fate of MSCs represent a novel strategy in regenerative medicine.
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Cationic polymers can modulate the differentiation of MSCs via ephrinB2/EphB4 signaling.
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pHM3 compromises the osteocyte differentiation altering ephrinB2/EphB4 interaction.