Absence epilepsy: Continuum of clinical presentation and epigenetics?

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• 作者：Laura M. Guilhoto ^{lauragui@gmail.com lauragui@usp.br}
• 关键词：Absence seizure ; Generalized epilepsy ; Treatment ; Prognosis ; Classification ; Nosology
• 刊名：Seizure
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：44
• 期：Complete
• 页码：53-57
• 全文大小：287 K
• 卷排序：44

文摘

Several nosological entities present absence seizures according to different proposals of epileptic syndromes classification. Although other antiepileptic drugs are effective, ESM is the choice for treatment of childhood absence epilepsy. There is risk of academic failure and attentional deficits that persist despite seizure freedom in children with absence epilepsy. In adults prognosis is influenced by rare clinical presentations such as perioral and eyelid myoclonic components that poses worse outcome. Overall prognosis depend on age of onset, presence of other seizure types and response to initial treatment.