Antimicrobial activity of crude extracts prepared from fungal mycelia

详细信息    查看全文

• 作者：Andriy Synytsya¹ ; Jutamart Monkai² ; Roman Bleha¹ ; Anna Macurkova³ ; Tomas Ruml³ ; Juhee Ahn⁴ ; Ekachai Chukeatirote² ; ^{ekachai@mfu.ac.th}
• 关键词：Antimicrobial activity ; Disc diffusion ; Fungal mycelia ; Partitioned extracts
• 刊名：Asian Pacific Journal of Tropical Biomedicine
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：7
• 期：3
• 页码：257-261
• 全文大小：633 K
• 卷排序：7

文摘

To evaluate the in vitro antimicrobial property of three different partitioned extracts (petroleum ether, ethanol and water) prepared from some fungal mycelia.MethodsSeven fungal mycelia were prepared, initially extracted with acidified ethanol (0.2 mol/L HCl in 80% ethanol), yielding the raw crude extracts. The obtained extracts were then further partitioned with petroleum ether (F1), ethanol (F2) and water (F3). All the fractions were tested for antimicrobial activity using the disc diffusion assay.ResultsOur data showed that all the fractions could inhibit the testing bacteria. However, the inhibitory activity was found to be dependent on (i) the fungal strains used; (ii) the solvent extracted; and (iii) the testing bacteria assayed. In general, the ethanolic extracts (F2) derived from all fungi displayed highest inhibitory activity against the testing bacteria except for Chaetomium sp.ConclusionsThe findings of the present study concluded that the extracts prepared from the fungal mycelia had the bioactive compounds with antibacterial property. This study is a pioneering work and further study should be carried out for development of the new drug leads.