Melatonin from slow-release implants did not influence the gene expression of the lipopolysaccharide receptor complex in the choroid plexus of seasonally anoestrous adult ewes subjected or not to a systemic inflammatory stimulus

详细信息    查看全文

• 作者：M. Kowalewska^a ; ¹ ; A. Szczepkowska^a ; A.P. Herman^b ; M.T. Pellicer-Rubio^c ; M. Jałyński^d ; J. Skipor^a ; ^{j.skipor@pan.olsztyn.pl}
• 关键词：Toll-like receptors ; CD14 ; Lipopolysaccharide ; Choroid plexus ; Melatonin implantation ; Ewes
• 刊名：Small Ruminant Research
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：147
• 期：Complete
• 页码：1-7
• 全文大小：875 K
• 卷排序：147

文摘

Lipopolysaccharide receptor complex (TLR4, MD-2, CD14) expression in choroid plexus. Lipopolysaccharide (LPS) increases mRNA expression for TLR4 and CD14 but no for MD-2. Plasma LPS binding protein (LBP) level increases 4–6 h after LPS treatment. No effect of melatonin implantation on LBP and mRNA expression for TLR4, MD-2, CD14.