Ultrasensitive and universal fluorescent aptasensor for the detection of biomolecules (ATP, adenosine and thrombin) based on DNA/Ag nanoclusters fluorescence light-up system
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- 作者：Ying Zhu ; Xiao-chun Hu ; Shuo Shi ; shishuo@tongji.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Ru-ru Gao ; Hai-liang Huang ; Yan-yan Zhu ; Xiao-yan Lv ; Tian-ming Yao ; tmyao@tongji.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aptamer ; DNA&ndash ; Ag NCs ; Guanine-enhanced ; Fluorescence
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：79
- 期：Complete
- 页码：205-212
- 全文大小：1807 K
文摘
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This method achieved success in detecting three different biomolecules both in PBS and FBS.
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A label-free, low-cost and enzyme-free biosensor is developed for biomolecule detection.
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Results for FBS samples demonstrated that our biosensor is applicable in real samples.
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This assay is universal by re-building or modifying DNA sequences.