Membrane disruption and DNA binding of Staphylococcus aureus cell induced by a novel antimicrobial peptide produced by Lactobacillus paracasei subsp. tolerans FX-6
详细信息 查看全文
- 作者：Jianyin Miaoa ; b ; Jianliang Zhoua ; Guo Liua ; Feilong Chena ; Yunjiao Chena ; Xiangyang Gaoa ; William Dixonb ; Mingyue Songb ; Hang Xiaob ; hangxiao@foodsci.umass.edu" class="auth_mail" title="E-mail the corresponding author ; Yong Caoa ; caoyong2181@scau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antimicrobial peptide ; Staphylococcus aureus ; Cell membrane ; DNA ; Antimicrobial mechanism
- 刊名：Food Control
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：609-613
- 全文大小：1097 K
文摘
- •
Investigated the antimicrobial mechanism of peptide F1 from Tibetan kefir against Staphylococcus aureus.
- •
Revealed that peptide F1 can cause damages to bacterial cell membrane that lead to leakage of cellular content.
- •
Revealed that peptide F1 can bind to bacterial DNA, which leads to disruption of vital cellular functions.