Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population
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- 作者：Rui Zhanga ; b ; Yan Bia ; b ; Weibo Niua ; b ; Xiaoye Huanga ; b ; Shiqing Chena ; b ; Xingwang Lia ; b ; Xi Wua ; b ; Yanfei Caoa ; b ; Fengping Yanga ; b ; Lu Wanga ; b ; Weidong Lia ; b ; Yifeng Xub ; Lin Hea ; b ; Tao Yua ; b ; yutao@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Guang Hea ; b ; heguang@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Association ; 5-HT1A ; 5-HT2A ; Schizophrenia ; Major depressive disorder
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：2 December 2016
- 年：2016
- 卷：635
- 期：Complete
- 页码：39-43
- 全文大小：603 K
文摘
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We investigated the association of 5-HT1A and 5-HT2A polymorphisms with both schizophrenia and major depressive disorder.
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The rs10042486 in 5-HT1A demonstrated significant difference between schizophrenia patients and controls.
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The 5-HT1A might be associated with schizophrenia in Chinese Han population.
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The rs1364043 and rs17289304 involved in our association study were explored for the first time.